What we do

We Transform Healthcare.

The Center for Health Systems Innovation (CHSI) at Oklahoma State University exists to solve the hardest problems in healthcare, where need is greatest, resources are scarce and traditional models fall short.

For more than a decade, CHSI has operated at the intersection of data, technology and real-world care delivery, building and deploying solutions that improve outcomes for rural and Native American communities while generating insights that can scale nationally.

Predictive Health Analytics & AI

CHSI is a national leader in applying advanced analytics and AI to complex healthcare challenges. We develop algorithms to improve decision-making processes and clinical outcomes.

Through our Predictive Medicine Group, we leverage large-scale, longitudinal real-world clinical datasets to:

• Predict disease onset and progression
• Identify high-risk patients earlier
• Enable proactive, personalized interventions

Rural & Tribal Health Innovation

We create solutions to transform patient care with an intensive focus on rural primary care and communities. We design, test and implement solutions to clearly defined problems in rural primary care clinics and hospital settings.

Through long-standing partnerships with rural clinicians and hospitals, tribal health systems and state agencies, we:

• Pilot new care models in real-world rural environments
• Deploy technology that works with limited resources and workforce constraints
• Co-design solutions with communities, not for them

Technology Evaluation & Deployment

CHSI serves as a trusted innovation partner for innovators, entrepreneurs, healthcare providers, payers and policymakers seeking to identify and deploy best-in-class innovations.

Our work includes:

• Source, build and evaluate emerging healthcare technologies
• Run structured pilots and proof-of-concept programs
• Measure clinical, operational and financial impact
• Support adoption, integration and scaling

Policy, Payment & Practice Change

Healthcare transformation doesn't happen without alignment across policy, payment and practice.

CHSI works with state and national partners to:

• Inform data-driven health policy
• Design innovation platforms and public-private partnerships
• Align incentives to support sustainable care and payment models

Our role is often to translate between worlds by connecting policymakers, technologists, clinicians and communities around shared outcomes.

Rural Oklahoma Network

ROK-Net

ROK-Net is CHSI's flagship rural innovation network, linking rural hospitals, clinics, tribal health systems and community partners across Oklahoma.

Through ROK-Net, CHSI:

• Pilots new care models and technologies in real-world rural settings
• Enables rapid testing and feedback loops with frontline providers
• Deploys solutions designed for workforce constraints, limited connectivity and complex patient needs

ROK-Net allows innovators to move beyond theory and into practice while allowing rural partners to tailor and access best-in-class solutions without bearing disproportionate risk.

Cross-Sector Collaboration

Oklahoma Business Collective on Health

The Oklahoma Business Collective on Health brings together employers, health system leaders, innovators and policymakers around a shared goal: improving health outcomes while bending the cost curve.

The Collective serves as a neutral, action-oriented forum to:

• Identify priority health challenges impacting the workforce
• Evaluate and pilot innovative solutions
• Align employers, providers and payers around measurable outcomes
• Translate innovation into sustainable, scalable adoption

By engaging the business community as a force for health system change, the Collective accelerates solutions that improve access, affordability and outcomes, benefiting both employers and communities.

Let's Work Together

Impact at Scale Requires Collaboration.

If you are a healthcare leader, policymaker, researcher, technologist, student or organization committed to improving rural and Native American health, we would welcome the conversation.